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Senolytic FOXO4-DRI can inhibit FOXO4 binding by disrupting the p53-FOXO4 interaction and selectively cause apoptosis via p53 nuclear exclusion in senescent cells and aging mouse models, which may be a promising approach for preventing senescence 11

Oxidative free radical damage is what makes us age

SCFAs, especially butyrate, strengthen the integrity of the gut barrier, reducing intestinal permeability and systemic inflammation

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Oxidative stress is an imbalance between free radicals and antioxidants in your body